Curare is a plant extract used by indigenous tribes in central and south america as a paralyses poison for hunting. Curare binds to ach receptors, but does not open the associated channels. What process in the motor unit is affected by curare? how would this affect muscle contraction?.



Answer :

Curare will only affect muscles with ACh receptors, paralyzing them.

Curare is a plant extract that is toxic. The molecular structure of curare molecules is similar to that of the neurotransmitter ACh. The chemically gated ion channels in the motor end plate have an ACh receptor site that curare can bind to.

Curare will bind to the receptor site, but it won't activate the ion channel, preventing any ions from passing through. Only muscles with ACh receptors will be paralyzed by Curare. This is how curare poisoning symptoms will seem. Therefore, curare will only affect muscles with ACh receptors, paralyzing them.

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