A person contracts a virus which destroys the white blood cells and, as such, becomes prone to infections. In this case, the signaling pathway which gets affected is NF-κB pathway.
The immune system is responsible for recognizing the invaders by their antigens, which are mostly proteins that are present on the surface of the invading cells. Every cell in the body has its own specific antigens, and a individual's cell carries “self-antigens” that are unique to that individual only and act as antigens to other individual.
An elevation in the level of lymphocytes is an indication of the condition known as lymphocytic leukocytosis. This condition may occur as a result of a virus or any other infection, such as tuberculosis.
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