in drosophila, an ncrna called rox is involved in dosage compensation. rox is part of the msl complex, which binds to the x chromosome and recruits histone-modifying enzymes to the chromatin. rox is required for the msl to bind to the x chromosome. what function is this ncrna playing?



Answer :

In Drosophila, an ncRNA plays a crucial role in directing Rox RNA and its non-coding genes for protein production.

RoX RNA can be a non-coding RNA (ncRNA) shown inside the male-specific dangerous (MSL) complex and is required for sex estimation compensation in Drosophila.

This can be fulfilled by the MSL complex official to the X chromosome and inciting histone H4 lysine 16 acetylation and licenses for the course of action of euchromatin. These ncRNAs were, to start found in RNA removed from neuronal cells.

Two roX RNAs have been recognized inside the MSL complex from Drosophila melanogaster and have shown up to be directed over different drosophila species.

The two roX RNAs, known as roX1 and roX2 have been shown up to differentiate in the basic course of action and course of action length but despite these contrasts, they both contain an MSL definitive area and are essentially redundant.

Cloning roX qualities and resulting gathering course of action from a few unmistakable drosophila species recognized some directed districts and it was moreover taken note that roX RNA is because it appeared in male flies.

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