a technologist is performing a body fluid analysis on a csf specimen recently received in the laboratory. four csf tubes were sent to the body fluids bench. the tech notices that all four specimens seem moderately blood tinged equally. moderate xanthochromia was also noted. what is the most likely reason for these findings?



Answer :

The most common cause of xanthochromia, which manifests as a yellow, orange, or pink staining of the CSF, is the breakdown of haemoglobin into oxyhemoglobin, methemoglobin, and bilirubin as a result of RBC lysis.

Xanthochromic CSF: Is it typical?

The yellowish staining of a centrifuged CSF specimen's supernatant is known as xanthochromia. It is abnormal and arises from the breakdown pigments oxyhemoglobin, bilirubin, and methemoglobin being released from RBC lysis into the CSF during Xanthochromia therapy. Treatment for xanthochromia entails addressing the underlying cause. If xanthochromia in the CSF indicates that the patient has a subarachnoid haemorrhage, they may have magnetic resonance imaging (MRI), CT angiography, or be sent immediately to the hospital for treatment.

A issue with the central nervous system is suggested by an abnormal protein level in the CSF. A tumour, haemorrhage, nerve irritation, or damage may all be indicated by an elevated protein level.

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