Describe how oxygen and carbon dioxide are transported in the blood, and explain how their loading and unloading is affected by temperature, ph, bpg, and pco2.

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18-10-2022
Biology

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Describe how oxygen and carbon dioxide are transported in the blood, and explain how their loading and unloading is affected by temperature, ph, bpg, and pco2.

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tutorconsortium31 tutorconsortium31 · Answer 1 · 2022-11-01T04:19:16-04:00

Both chemically and physically dissolved in haemoglobin, oxygen is transported in the blood. Blood proteins bind to carbon dioxide chemically as carbamino compounds, physically as bicarbonate, and physically as dissolved carbon dioxide.

What is Loading and unloading of CO2 and Oxygen ?

When 2,3-BPG binds to haemoglobin, oxygen is released. Additionally, 2,3-BPG lessens hemoglobin's affinity for oxygen. 2,3-BPG binds to haemoglobin as it is being unloaded in our tissues, favouring the unloading of oxygen.

Increased blood temperature causes hemoglobin's affinity for oxygen to decrease, which causes the Oxygen-Hemoglobin Dissociation Curve, which is detailed in Oxygen Transport, to move to the right. As a result, higher temperatures cause haemoglobin to release oxygen more quickly.

An increase in carbon dioxide partial pressure causes oxygen to dissociate from haemoglobin, which tends to release oxygen at the tissue level, increasing the amount of oxygen released.

Carbon dioxide is more easily released from haemoglobin thanks to oxygen loading. The Haldane effect is what is meant by this. Carbon dioxide loading makes oxygen unloading easier as the pH drops. The Bohr effect refers to the interplay between hemoglobin's affinity for hydrogen ions and its affinity for oxygen.

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