A group of mutations, known as MT-ND1, have been identified in mitochondrial DNA. These mutations are associated with a number of debilitating diseases stemming from the production of nonfunctional proteins in the mitochondria.

Which of the following cellular deficiencies would most likely be related to these MT-ND1 mutations?
a. The cell is unable to synthesize most proteins required for normal cell functions.
b. The cell is unable to break down toxic materials and would accumulate large volumes of these materials.
c. The cell is able to synthesize proteins, but the proteins would not fold properly and would not contain the correct molecular tags for export from the cell.
d. The cell is unable to complete reactions related to electron transport and ATP production.

Question

18-10-2022
Biology

Answered

A group of mutations, known as MT-ND1, have been identified in mitochondrial DNA. These mutations are associated with a number of debilitating diseases stemming from the production of nonfunctional proteins in the mitochondria.

Which of the following cellular deficiencies would most likely be related to these MT-ND1 mutations?
a. The cell is unable to synthesize most proteins required for normal cell functions.
b. The cell is unable to break down toxic materials and would accumulate large volumes of these materials.
c. The cell is able to synthesize proteins, but the proteins would not fold properly and would not contain the correct molecular tags for export from the cell.
d. The cell is unable to complete reactions related to electron transport and ATP production.

Answer :

Other Questions

Select the correct answer from each drop-down menu. Compared to its surroundings, the concentration of solutes is low inside a cell. So, the cell is in a v solu

what is most likely responsible for this result? what is most likely responsible for this result? the embryo passes through multiple rounds of the cell cycle, b

Which molecule is the source of basic material used for the production of ATP in the Kreb Cycle? A. NADH B. Oxygen C. Water D. FADPH

Answer all please I need it asap 1. A(n) _____________________ transports electrons, along with their energy, to another molecule. 2. What is the equation for p

Nhóm ngành sinh học cơ bản không có nghànhA.y học B. Dược học C. Pháp y C. Thủy sản

A01 B01 C01 D01 E01 F01 G01 Chicken ID A. 234.6 B. 230 OC 231 234 229 235 231 229 What is the median number of eggs laid in a year? 222 262 Number of eggs

the diffusion of hydrogen ions down their concentration gradient allows; A. H+ ions to serve as the final electron acceptor B. energy to be released as H+ ions

which is correct regarding the krebs cycle reactions? group of answer choices a) take place in the cytosol of human cells b) generate atp directly by substrate

Paruljain Paruljain · Answer 1 · 2022-10-26T07:48:57-04:00

The cell is unable to complete reactions related to electron transport and ATP production would most likely be related to these MT-ND1 mutations. So the correct option is (d).

Rare mutations in the MT-ND1 gene are responsible for stroke-like episodes, lactic acidosis, and mitochondrial encephalomyopathy (MELAS). A small number of MELAS cases originating from mutations in the MT-ND1 gene have been described, while the majority of MELAS cases are caused by mutations in other mitochondrial genes.

The proteins in the mitochondrion's inner membrane are involved in the electron transport chain and the generation of ATP. Reduced ATP generation in the mitochondrion is probably caused by dysfunctional proteins.

Therefore, senescent dysfunction of long-lived post-mitotic cells, such as neurons, cardiac myocytes, skeletal muscle fibers, and RPE, is primarily triggered by decreased ATP generation and increased oxidative stress. The cell is unable to complete reactions related to electron transport and ATP production would most likely be related to these MT-ND1 mutations. So the correct option is (d).

Learn more about MT-ND1 mutations here:

https://brainly.com/question/14799128

#SPJ4