Answer :
The property that prevents the ligands of cell-surface receptors from entering the cell is The molecules are hydrophilic and cannot penetrate the hydrophobic interior of the plasma membrane.
What is a Lingand?
A ligand is said to be an ion or molecule, that donates a pair of electrons to the central metal atom or ion thereby leading to the formation of a coordination complex. The word ligand is from Latin, which means “tie or bind”. Ligands can be anions, cations, and neutral molecules.
Here's the complete question:
What property prevents the ligands of cell- surface receptors from entering the cell?
a. The molecules bind to the extracellular domain.
b. The molecules are hydrophilic and cannot penetrate the hydrophobic interior of the plasma membrane.
c. The molecules are attached to transport proteins that deliver them through the bloodstream to target cells.
d. The ligands are able to penetrate the membrane and directly influence gene expression upon receptor binding.