Numerous indigenous people were exposed to diseases during the Spanish missions, which allowed the diseases to spread to the American Indians. So, A is the best choice for us.
Despite being impacted before the introduction of missions, the buildings made it easier for rodents to enter household spaces and quickly spread disease.
Typhus, the measles, and smallpox were a few of the most widespread ailments. Numerous locals were living in small quarters with subpar diet and cleanliness.
Tens of thousands of Native Americans perished as a result of this mission from disease, war, and forced labor. The introduction of "Old World" illnesses that wiped off the indigenous inhabitants was the result of Spanish contact with those groups.
Smallpox and measles were among the illnesses for which the native population lacked protection.
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