john and sue are expecting a child, but are concerned about a rare autosomal recessive disease that is present in both of their families. in the pedigree, john is represented as individual iii‑11 and sue is represented as individual iii‑12; both are unaffected. john's sister, iii‑10, and sue's brother, iii‑13, both do not show evidence of the disease, but john's paternal grandmother and sue's maternal grandfather both had the disease. assign the appropriate symbol to each individual in the pedigree.

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13-09-2022
Biology

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john and sue are expecting a child, but are concerned about a rare autosomal recessive disease that is present in both of their families. in the pedigree, john is represented as individual iii‑11 and sue is represented as individual iii‑12; both are unaffected. john's sister, iii‑10, and sue's brother, iii‑13, both do not show evidence of the disease, but john's paternal grandmother and sue's maternal grandfather both had the disease. assign the appropriate symbol to each individual in the pedigree.

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tutorconsortium215 tutorconsortium215 · Answer 1 · 2022-09-15T12:47:13-04:00

Here is the family tree. I found exercises online.

Those without icons are II-5, II-6, II-8, III-10, III-11, III-12, III-13.

Her individual II-5 will be a half black/half white square. Square because the introductory text states that it is John's paternal grandmother (I-2) who has the disease. His mother contracted the disease, so she inevitably passed on an allele that was the disease allele, and his father did not have or exhibit the disease, so he was half black/half white. Yes, meaning that John's father (II-5) received only the normal allele.

Individual II-6 has a question mark in a circle. If John's father is individual II-5, she is John's mother, so circle. A question mark because there is no information about how her disease manifests itself in her.Her sister received two alleles for the disease.

Each her II-8 has a half black/half white circle. If her father is individual II-7 (square), she is Sue's mother, so circle. Because her father had the disease, he inevitably passed on an allele that was the disease allele, and her mother did not have the disease and showed no symptoms, so half black/half was white, and Sue's mother (II-8) received only one normal allele. .

The III-10 would have a circled question mark on it. She is a circle because, as said in the introduction, she is John's sister. Because we are unable to determine whether she carries all disease alleles or none at all, we have put a question mark beside her name. Since her mother is only a carrier of one disease gene, she might have inherited a disease allele from either her father or her mother; but, if her mother has the condition, she would unquestionably have inherited a disease allele from her mother and not from her father.

John, Individual III-11 has a question mark in the square. John is a man, so he is square. A question mark because we cannot determine whether he has the disease allele or no disease at all. From the introductory text, we conclude that he has no evidence of the disease, but the If he only has the allele, he may have acquired the disease allele from his father or mother. From his father if his mother is ill.

Sue, Individual III-12 has a question mark in a circle. Maru because it's a woman's Sue. A question mark because it is not possible to determine whether she has the disease allele or no disease at all. If she is a carrier, she may have received the disease allele from her mother, making her a carrier as well. She has a normal allele from her mother. She received her only one normal allele from her father.

Individuals III-13 are marked with a question mark in the square. According to the introductory text, he is Sue's brother, hence the square. A question mark because we cannot determine if he has the disease allele or not the disease at all. If he is a carrier of the gene, he may have received the disease allele from his mother, making him a carrier as well. received the allele from his mother. He received only one normal allele from his father.

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