Answer :
p53 is activated when a DNA get damage which result in production of a Cdk inhibitor is preventing the cells from continually progressing through the cell cycle.
- Through the phosphorylation of the target genes, such as the tumour suppressor protein retinoblastoma, the synthesis of cyclin/CDKs regulates the cell-cycle progression.
- Cyclins collaborate with an enzyme family known as the cyclin-dependent kinases to control the cell cycle's activities (Cdks). A Cdk that is not bound to a cyclin is inactive, but when it is, it becomes a functioning enzyme that can alter target proteins.
- Mitosis and interphase are the two phases that make up the cell cycle. The majority of the cell's activity during interphase is devoted to the tasks that distinguish it from other cells. The stage of the cell cycle known as mitosis occurs when a cell divides into two daughter cells.
To learn more about cell cycle.
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