Yes , because many species can have planktonic growth or live within a biofilm, and biofilm can contain a single species.
A biofilm is comparable to a well-fortified cave where microorganisms hibernate. Antibiotics are blocked by the matrix's barrier. But the entrance of food and oxygen is also restricted by this protective barrier. The bacteria in the biofilm's depths will begin to starve.
There can be four effects of biofilm, generating chronic infection, the modulation of host immune response, antimicrobial drug resistance and contamination of medical devices.
So , yes it is possible.
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