An immune response to a tissue graft will differ from an immune response to a bacterium because _______. A. MHC molecules of the donor may stimulate rejection of the graft tissue, but bacteria lack MHC molecules B. the tissue graft, unlike the bacterium, is isolated from the circulation and will not enter into an immune response C. a bacterium cannot escape the immune system by replicating inside normal body cells D. the graft will stimulate an autoimmune response in the recipient

Question

23-08-2022
Biology

Answered

An immune response to a tissue graft will differ from an immune response to a bacterium because _______. A. MHC molecules of the donor may stimulate rejection of the graft tissue, but bacteria lack MHC molecules B. the tissue graft, unlike the bacterium, is isolated from the circulation and will not enter into an immune response C. a bacterium cannot escape the immune system by replicating inside normal body cells D. the graft will stimulate an autoimmune response in the recipient

Answer :

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tushargupta0691 tushargupta0691 · Answer 1 · 2022-08-26T20:47:02-04:00

An immune response to a tissue graft will differ from an immune response to a bacterium because MHC molecules of the donor may stimulate rejection of the graft tissue, but bacteria lack MHC molecules

What is referred to as tissue graft rejection?

Graft rejection after solid organ transplantation is a complicated process involving a variety of immunological mediators.

T cells and cytokines have been shown to play important roles in many animal models of graft rejection, as well as in human transplant patients.

Prophylactic therapy of graft rejection using immunosuppressive medicines such as cyclosporine and mycophenolate mofetil, as well as reduction of cytokine synthesis and activity by glucocorticoids and anti-IL2R antibodies, is the current standard of care.

In certain cases, the antibody is obviously engaged in graft rejection, but its significance in acute and chronic rejection is unknown.
Transplant biologists continue to strive for specific modulation of these immune responses and the subsequent graft tolerance in adults.

Hence, the correct answer is option A

Learn more about graft rejection here,

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