The [H₂CO₃] / [HCO⁻₃] ratio in normal blood is 20
Steps
According to Henderson-Hasselbulch equation:
pH = pKa + Log{[H₂CO₃] / [HCO⁻₃]}
7.4 = 6.1 + Log{[H₂CO₃] / [HCO⁻₃]}
Log{[H₂CO₃] / [HCO⁻₃]} = 7.4 - 6.1
1.3=Log{[H₂CO₃] / [HCO⁻₃]}
[H₂CO₃] / [HCO⁻₃] =20
The [H₂CO₃] / [HCO⁻₃] ratio in normal blood is 20
How are buffers defined?
"A buffer is an aqueous solution that prevents pH changes when an acid or base is added." Additionally, a buffer's pH is not greatly altered by the addition of water or by allowing water to evaporate from a buffer. Fundamentally, buffers are made up of a pair of weak acids and their conjugate bases or a pair of weak bases and their conjugate acids.
How does the buffer function?
According to our definition, a buffer is a conjugate acid-base mixture that can withstand pH shifts when small amounts of strong acids or bases are introduced.
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