The first articles about the detection of poison in the body were published in the year 1814.
It was the Spanish chemist Mathieu Orfila, who published a treatise on poisons and their detection, the first book of its kind.
The study of poison or the scientific study of poison, is called toxicology. It was coined in the 17th century. Toxicology was originally an empirical science, which did not involve any volumetric science until chemistry and analytical science came into being.
The Marsh Test was the first use of toxicology in a jury trial, though the first publicly documented use or the first time evidence from forensic toxicology was introduced in Tulle, France in 1840.
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