A clinical trial was conducted to test the effectiveness of a drug for treating insomnia in older subjects. Before treatment, 21 subjects had a mean wake time of 103.0 min Aher treatment, the 21 subjects had a mean wake time of 76.7 min and a standard deviation of 24.4 min. Assume that the 21 sample values appear to be from a normally distributed population and construct a 99% confidence interval estimate of the mean wake time for a population with drug treatments. What does the result suggest about the mean wake time of 103.0 min before the treatment? Does the drug appear to be effective?