Activity 5
Using the text above describing stem cells and endosteum as well as the chart below showing
cellular details, construct a sample of bone marrow to reflect the scenarios described in A, B,
and C below. The cells can be moved, resized, and rotated as needed.
Cells:
Adipocyte
MSCs
Multipotent stem cells
Give rise to:
Adipocytes
Osteoblasts
Fibroblasts
HSCS
Multipotent stem cells
Give rise to:
Erythrocytes
White blood cells
Megakaryocytes
Fibroblast
Neutrophil
Erythrocyte
Osteoblast
Endothelial Cell
Lymphocyte
Megakaryocyte
Reticular Cell
"If Only These Bones Could Talk" by Ashley E. Rhodes
NATIONAL CENTER FOR CASE STUDY TEACHING IN SCIENCE
A. Construct a sample of bone marrow within the medullary cavity of a long bone from a
healthy, pre-pubescent juvenile. An outline of trabeculae has been provided for spatial
reference. Overlay the stem cells, their products, and blood vessels on the trabeculae.
53%
pires Servier, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=82640931
w
uct a sample of bone marrow within the medullary cavity of a long bone from a
healthy adult animal. Overlay stem cells, their products, and blood vessels on the trabeculae.
Laboratoires Servier, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=82640931