Which of the following statement(s) are correct regarding point and frameshift gene mutations?
Responses

A Frameshift mutations arise from the insertion or deletion of nucleotide and are more serious than a point mutation.

B Frameshift mutations arise from the substitution of a nucleotide and are less serious than a point mutation.

C Frameshift mutations always result in a change to the protein. D Point mutations arise from the substitution of a nucleotide and are less serious than a frameshift mutation.

E Point mutations arise from the insertion or deletion of a nucleotide and are more serious than a frameshift mutation.

F Point mutations always result in a change to the protein.