One mutation inALAS2that is associated with protoporphyria is a four-nucleotide deletion. Theprotein expressed from the mutant allele is20amino acids shorter than the wild-type protein.
5.Which of the following best explains why a shortened protein is produced? TT
a)The mutation disrupts the start codon, preventing the ribosome from beginningtranslation.
b)The mutation introduces a premature stop codon, causing translation to end early.
c)The mutation changes the gene’s regulatory region, causing unregulated geneexpression.
d)The mutation affects posttranscriptional modifications by preventing the removal ofintrons