Puzzle #2

Use the digits -9 to 9 to complete the puzzle below. Try all the combinations. But as you begin doing that, you will realize that in some cases you are looking for factor combinations with a particular sum or difference. You will see that some numbers have to be greater than a particular value in order to produce the product you are looking for. Show your work to confirm your solution.

( i dont normally ask questions on here but this has been frying my brain for the last hour. help would be appreciated.)