Metaphase plate Replication of genetic material results in chromosomes consisting of two Prophase A cell in metaphase has chromosomes located in the of the cell. Telophase Cytokinesis Division of the cytoplasm to produce two daughter cells is called Mitosis Double-stranded chromosomes separate during the stage of mitosis. S During interphase, DNA replication occurs in the phase. Centromere Microtubules called attached to chromatids and pull them apart. Anaphase Chromatids Chromosomes become visible during the stage of mitosis Spindle fibers The last stage of mitosis is Division of the nuclear material is called Matching chromatids are held together by a