Innate defenses are present at birth and provide mostly nonspecific resistance to infection, whereas adaptive defenses are specific defenses that must be acquired.
- Innate or general defences stop or restrict the movement, invasion, and spread of microbes and other environmental threats. These defences frequently work independently of other defences to eliminate germs and avoid infection.
- However, occasionally the non-specific defences require assistance from the adaptive immune system. The initial line of protection is comprised of undamaged skin and mucosae, which are known as nonspecific defences.
- The second line of defence is triggered when germs enter the skin or mucosae. Internal defences, such as phagocytes and antibacterial proteins, are necessary for this.
- The most crucial mechanism in the second line of defence is inflammation. Mechanical barriers that cover bodily surfaces and chemical compounds that interact with invasive infections are two examples of nonspecific defences.
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