an artificial chromosome created by combining centromeres, telomeres, and origins of replication from yeast.origin of replication in yeast.a fluorescent dna probe hybridizes to chromosomal dna on a slide to locate a sequence in the genome.regions of a chromosome that are distinguished by staining differences when treated with giemsa stain.a beadlike structure consisting of dna wound around histone proteinsplexes of dna and protein located in the eukaryotic nucleus.enzyme that elongates specific repetitive sequences at the ends of linear chromosomes.protein that protects cohesin of the centromere region from cleavage during meiosis i.a specialized structure composed of dna and proteins that is the site at which chromosomes attach to the spindle fibers