Answer :
In an E2 reaction, the most frequent reactants are alkyl halides and alcohols.
What is E2 reaction ?
- In an E2 reaction, the most frequent reactants are alkyl halides and alcohols. Here are some E2 response examples. Alkenes are formed through the removal of alkyl halides. Alkenes are formed through the removal of alcohols.
- The unusual alignment of the -hydrogen and the leaving group in the transition state is the cause of the stereochemistry in E2 reactions. The prerequisite is that these two groups be located in the same plane - periplanar: A syn periplanar molecule has the -hydrogen and the leaving group on the same side of the molecule.
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Answer:
In syn elimination, the base attacks the β-hydrogen on the same side as the leaving group.
Explanation:
E2 Stereochemistry
In anti elimination, the base attacks the β-hydrogen on the opposite side of the leaving group. It has been experimentally determined that E2 elimination occurs through an anti mechanism.
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