how is an hfr chromosome formed? how is an hfr chromosome formed? by a specific deletion mutation in the bacterial chromosome by a specific gene duplication in the f-plasmid by integration of the f-plasmid into the bacterial chromosome by a point mutation in a bacterial gene that is essential for conjugation request answer



Answer :

An IS element on the F-plasmid and the identical IS element on the host chromosome can recombine to create Hfrs. Many bacterial chromosomes include multiple IS insertions. Consider the wild-type E.

Because they frequently transfer chromosomal genes, bacteria with an F-plasmid incorporated into the chromosome are referred to as Hfr strains.

A bacterium having a conjugative plasmid (such as the F-factor) incorporated into its chromosomal DNA is known as a high-frequency recombination cell (Hfr cell), sometimes known as a Hfr strain. The incorporation of the plasmid into the cell's chromosome is by homologous recombination. F plasmids, not the complete chromosome, are often transferred to the recipient bacterium during bacterial conjugation. Those bacteria are referred to as F+ strains or donors if they carry the F plasmid. They can create sex pili and transfer plasmids to other bacteria that take them in.

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