10. In which of the following situations is a biotechnologist most likely to decide to use directed evolution as an enzyme engineering technique as opposed to rational design?
A) When a structure of the
enzyme is available to aid engineering
B) When the enzyme can only be
screened in a low throughput manner
C) When the enzyme mechanism
is understood and provides insight to engineering
D) When current data allows
molecular modelling techniques to be used predictively
E)When none of the above are true