genetic diseases sometimes occur at high frequency in populations that are, or once were, relatively isolated. for example, an enzyme deficiency called hereditary tyrosinemia occurs at an unusually high rate in the chicoutimi region in canada. a condition called porphyria is unusually common in south africans of dutch descent. why are genetic diseases so common in isolated populations?

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05-10-2022
Biology

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genetic diseases sometimes occur at high frequency in populations that are, or once were, relatively isolated. for example, an enzyme deficiency called hereditary tyrosinemia occurs at an unusually high rate in the chicoutimi region in canada. a condition called porphyria is unusually common in south africans of dutch descent. why are genetic diseases so common in isolated populations?

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Baraka1 Baraka1 · Answer 1 · 2022-10-08T15:57:31-04:00

Genetic diseases are more common in isolated populations due to things like founder effect.

Founders effect is the situation when a small group of one specie colonize a new location and begin a new population. An offset of a a smaller group of species from a large group of species migrates and starts a new population to a different location. Over time, the resulting new subpopulation will have genotypes and physical traits similar to the initial small, separated group.

This migration tend to greatly reduce the gene pool and also genetic variation. In effect, it leaves the population at a higher risk of being prone to these genetic diseases.

Learn more about Founder's effect at:

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