Protein kinases generally regulate the activity of target proteins by transferring a phosphate group from atp to what kind of functional group on the target protein?

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12-09-2022
Biology

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Protein kinases generally regulate the activity of target proteins by transferring a phosphate group from atp to what kind of functional group on the target protein?

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tutorconsortium31 tutorconsortium31 · Answer 1 · 2022-09-14T16:33:05-04:00

Protein kinases generally regulate the activity of target proteins by transferring a phosphate group from ATP to hydroxyl group

What is Protein kinases ?

By phosphorylating particular amino acids with ATP as the source of phosphate, protein kinases (PTKs) are enzymes that control the biological activity of proteins. This results in a conformational change from an inactive to an active form of the protein.

Because of their crucial function in the signalling systems that drive the features of malignant cells, protein kinases are significant therapeutic targets in cancer.

Enzymes are impacted by protein kinases by altering their structure. By converting the enzyme's shape into an active conformation, they activate enzymes. By using the same technique of altering the proteins' conformation, they can also disable enzymes.

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