Which capillary type is the leakiest and has specialized cells known as kupffer cells associated with them?

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05-09-2022
Biology

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Which capillary type is the leakiest and has specialized cells known as kupffer cells associated with them?

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tutorconsortium215 tutorconsortium215 · Answer 1 · 2022-09-08T13:40:16-04:00

Sinusoid (Discontinuous) Capillaries

A unique variety of capillary, sinusoid capillaries are present in the endothelium and have quite big, open holes.

There are sinusoid blood veins in the lymph nodes, the adrenal glands, and even the bone marrow. Some cells do not have tight connections between them; these cells are typically found in the liver and spleen.

These tiny blood arteries, referred to as sinusoids, contain open pores as opposed to the continuous and fenestrated forms of capillaries. Contrary to sinusoid capillaries, which lack a diaphragm and only contain an exposed open pore, fenestrated capillaries have diaphragm-like structures that cover the pores.

The permeability of the capillary is increased by these open pores, and this permeability allows albumin and other small- and medium-sized proteins to enter and leave the bloodstream.

What are Kupffer cells used for?

Kupffer cells, sometimes referred to as stellate macrophages and Kupffer-Browicz cells, are specialized cells found in the liver's sinusoids lumen and are adhering to the endothelial cells that make up the blood channel walls. The majority of tissue-resident macrophages in the body are found in kupffer cells.
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