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What would you expect to happen if MPF (maturation-promoting factor) is introduced into immature frog oocytes that are arrested in G₂ ? (A) The cells would remain arrested in G₂ . (B) The cells would enter Go. (C) The cells would enter mitosis. (D) The cells would begin DNA synthesis.



Answer :

if MPF (maturation-promoting factor) is introduced into immature frog oocytes that are arrested in G₂ then the cells would enter mitosis.

  • Maturation-promoting factor (MPF) is a cell cycle regulatory element that, when injected into amphibian oocytes or treated with nuclei in a cell-free system, can trigger metaphase.
  • Maturation-promoting factor (MPF), also known as mitosis-promoting factor or M-Phase-promoting factor, is a cyclin-CDK complex identified in frog eggs. It promotes the cell cycle's mitotic and meiotic stages. By phosphorylating several proteins required during mitosis, MPF facilitates the transition from the G2 phase to the M phase. A phosphatase, which eliminates an inhibiting phosphate group introduced previously, activates MPF at the conclusion of G2

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